慢性压力和心血管健康:MESA和MASALA研究
Saaniya Farhan1, Laura A Colangelo2, Abigail Marie Gauen2
1Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL; Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA.
American journal of preventive medicine
|August 14, 2025
概括
高度的慢性压力与较低的心血管健康 (CVH) 评分有关. 这项研究没有发现压力与心脏病的变化之间的联系,强调了压力对心脏健康的直接影响.
科学领域:
- 心血管健康 心血管健康
- 心理社会因素 心理社会因素
- 流行病学 流行病学
背景情况:
- 慢性压力与个体心血管健康 (CVH) 指标有关,但其与整体CVH的关联需要进一步研究.
- 微小化的种族和民族群体承受着不成比例的压力负担,需要对不同人群中的压力和CVH进行研究.
研究的目的:
- 评估慢性压力与整体CVH之间的关联.
- 检查慢性压力与个人CVH指标之间的关系.
- 通过焦虑,抑郁和社会支持来调查潜在的适度.
主要方法:
- 在多民族动脉样硬化研究 (MESA) 和美国南亚人动脉样硬化调解者研究 (MASALA) (2000-2018) 中,来自7978名参与者的数据汇总.
- 线性回归用于评估慢性压力与生活必需八个CVH得分 (不包括睡眠) 的横截面/年化变化之间的关联.
- 对社会人口统计学因素进行调整的分析,并检查了潜在的调节因素 (焦虑,抑郁,社会支持).
主要成果:
- 与没有慢性压力的人相比,具有高慢性压力的人具有明显较低的并发CVH得分 (-2.71分).
- 慢性压力与CVH得分的年化变化之间没有发现显著的关联.
- 焦虑,抑郁和社会支持并没有缓解慢性压力和CVH之间的关联.
结论:
- 高度的慢性压力与当前的心血管健康有不良关联.
- 这些发现强调了慢性压力与整体健康结果之间的显著关系.
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