除了初级运动皮层之外,绘制皮层刺激性的方法 - 从认知神经科学,多式成像和临床应用的角度来看
Anna-Lisa Schuler1, Martin Tik2, Elisa Kallioniemi3
1Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Neuroscience and biobehavioral reviews
|August 14, 2025
概括
在整个大脑中非侵入性地映射大脑兴奋度是具有挑战性的,但可以实现的. 先进的神经成像技术与跨磁刺激 (TMS) 结合,为神经科学和临床应用提供准确,高分辨率的绘图.
科学领域:
- 神经科学是一个神经科学.
- 神经生理学 神经生理学
- 脑部成像 脑部成像
背景情况:
- 神经元刺激性对大脑功能至关重要,在神经精神疾病中受到干扰.
- 目前的非侵入性脑刺激性测量主要局限于运动皮层.
- 跨体磁刺激 (TMS) 深度透和单点刺激极限全脑映射.
研究的目的:
- 审查全脑兴奋度映射的最先进技术.
- 讨论在非侵入性大脑刺激性评估方面的进展.
- 探索它对神经科学和临床医学的影响.
主要方法:
- 讨论跨磁刺激 (TMS) 及其对全脑绘图的局限性.
- 突出了同步神经成像技术的作用,如脑电图 (EEG) 和功能磁共振成像 (fMRI).
- 探讨了替代刺激方法和休息状态活动调查.
主要成果:
- 神经成像,单独或与TMS,可以实现非侵入性,准确的全脑刺激性映射.
- 未来的方法承诺大脑活动的高时空分辨率.
- 进步将克服当前深度和单点刺激的局限性.
结论:
- 全大脑兴奋度映射正在迅速发展.
- 这将对基础神经科学和临床诊断产生重大影响.
- 改进的映射为理解和治疗神经精神疾病提供了关键的进步.
相关概念视频
Motor and Sensory Areas of the Cortex
4.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
4.6K
Somatosensation
38.5K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
38.5K
Somatosensory, Motor, and Association Cortex
915
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
915
Association Areas of the Cortex
6.3K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
6.3K
Overview of Somatic Sensory Pathways
5.4K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
5.4K


