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Updated: Sep 11, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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在荷尔蒙依赖性癌症中准CDK4和CDK6

Jessica R Bobbitt1, Ruth A Keri2

  • 1Department of Pathology School of Medicine, Case Western Reserve University, Cleveland, OH, United States; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, United States.

Vitamins and hormones
|August 14, 2025
PubMed
概括

选择性环素依赖性激酶4/6抑制剂 (CDK4/6i) 为癌症治疗提供了一种新方法,特别是对于雌激素受体阳性乳腺癌. 研究正在探索它们在其他激素驱动的癌症中的应用.

关键词:
乳腺癌是什么? 乳腺癌是什么在CDK4/6中使用.这是一种CDK4/6抑制剂.细胞循环的细胞周期荷尔蒙依赖的癌症 荷尔蒙依赖的癌症

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