在COVID-19患者儿童中量化COVID-19后症状和肺功能能力
Jeng-Hung Wu1, Ching-Chia Wang2, Yi Pan3
1Department of Medicine, National Taiwan University Hospital Jinshan Branch, New Taipei City, Taiwan; Department of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
在COVID-19后经历持续症状的儿童的疫苗接种率较低,睡眠相关疲劳增加. 年长的孩子报告疲劳更大,认知疲劳影响了6分钟步行测试的表现.
科学领域:
- 儿科肺病学 儿科肺病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 患有COVID-19的儿童往往有轻微但持续的肺部问题.
- 有限的研究存在于COVID-19后的有氧能力和儿童的症状严重程度.
- 这项研究量化了COVID-19后儿童的疲劳,呼吸障碍和肺功能.
研究的目的:
- 为了量化COVID-19后的疲劳,呼吸障碍和儿童的肺功能能力.
- 为了确定与COVID-19感染后持续症状相关的因素.
- 探索疲劳,认知功能和身体表现之间的关系.
主要方法:
- 一项针对COVID-19感染的6-12岁儿童的前性队列研究.
- 父母填写的问卷评估了疲劳 (儿科生活质量清单) 和呼吸障碍 (医学研究理事会修改呼吸障碍量表).
- 六分钟步行测试 (6MWT) 测量了肺功能容量.
主要成果:
- 在21名儿童中,有7名 (33%) 患有持续症状.
- 患有持续症状的儿童的疫苗接种率较低 (57%vs100%),睡眠相关疲劳率较高.
- 高龄与疲劳增加有关,认知疲劳与6MWT表现相关.
结论:
- 儿童的COVID-19后症状与较低的疫苗接种率和较高的睡眠相关疲劳有关.
- 年长的孩子会经历更严重的疲劳.
- 认知疲劳是影响肺功能的一个重要因素,用6MWT测量.
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