从国际肺癌查试验中吸取的教训; 风险人群值得进行早期检测查
Emily Stone1, Henry Marshall2, Pan-Chyr Yang3
1Department of Thoracic Medicine and Lung Transplantation, St Vincent's Hospital Sydney; and Melbourne School of Population and Global Health, University of Melbourne, Victoria, Australia; and School of Clinical Medicine UNSW Sydney, Sydney, NSW, Australia.
Respirology (Carlton, Vic.)
|August 14, 2025
概括
使用低剂量CT的肺癌查计划越来越受欢迎. 优化实施是高参与度和实现预测的肺癌负担减轻的关键.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 公共卫生 公共卫生
背景情况:
- 低剂量计算机断层扫描 (LDCT) 用于肺癌查 (LCS) 被广泛接受,得到随机对照试验 (RCT) 证据的支持.
- 有效实施肺癌查计划 (LCSPs) 对于最大限度地参与和实现预测的健康益处至关重要.
- 晚期肺癌治疗方案可以补充针对性治疗和晚期肺癌免疫疗法的进展.
研究的目的:
- 审查肺癌查的近期临床发展.
- 突出肺癌查 (LCS) 的当前问题.
- 讨论全球有效的肺癌查计划 (LCSP) 实施的推动因素和障碍,重点关注亚太地区.
主要方法:
- 关于肺癌查的已发表的临床试验和当代文献的综述.
- 分析各种司法管辖区的实施策略和结果.
- 专注于区域视角,特别是来自亚太地区的视角.
主要成果:
- 低剂量CT肺癌查被广泛接受,许多地区采用基于人口的方案.
- 最佳实施需要高参与率和质量保证,以确保有效的肺癌查计划.
- 最近的临床发展和正在进行的试验继续塑造LCS策略.
结论:
- 有效的肺癌查计划 (LCSPs) 对于利用低剂量CT查的好处至关重要.
- 解决实施的推动因素和障碍对于成功的全球和区域LCSP采用至关重要.
- 亚太地区为肺癌查实施带来了独特的挑战和机遇.
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