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Updated: Sep 11, 2025

Development of Compendium for Esophageal Squamous Cell Carcinoma
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DNA/RNA结合蛋白KIN17通过解决R循环诱导的非正规STING激活来支持食道癌症的进展

Zichao Wei1, Ning Zhao1, Lu Kuang1

  • 1State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.

Signal transduction and targeted therapy
|August 14, 2025
PubMed
概括

在食道状细胞癌 (ESCC) 中,DNA损伤反应 (DDR) 蛋白KIN通过解决R循环和抑制免疫力来促进癌症的进展. 抑制KIN激活了抗瘤免疫力,并提高了免疫治疗的有效性.

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