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Updated: Sep 11, 2025

Author Spotlight: Enhanced Histone PTM Isomer Identification Through LC-TIMS-ToF MS/MS and PASEF
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使用液体染色学对DNA混合物的测序――后活性等离子电子脱离解离质谱法

Takashi Baba1, Kaoru Karasawa2

  • 1Sciex: 71 Four Valley Dr., Concord, Ontario L4K 4 V8, Canada.

Analytical chemistry
|August 15, 2025
PubMed
概括

我们通过对电荷降低物种进行碰撞后激活来增强对DNA测序的电子脱离解离 (EDD) 灵敏度. 这种方法显著提高了片段强度,并实现了DNA混合物的100%序列覆盖率.

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