在荷兰患者中使用大麻,这些患者患有初级脑瘤
Vera Belgers1,2, Niek A Rietveld3, Philip C de Witt Hamer3,2
1Department of Neurology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Neuro-oncology practice
|August 15, 2025
概括
许多原发性脑瘤患者使用大麻来缓解症状或潜在的抗癌作用. 这凸显了对大麻研究的需要.
科学领域:
- 神经瘤学神经瘤学
- 大麻素科学 大麻素科学
- 症状管理 症状管理
背景情况:
- 癌症患者经常使用大麻来缓解症状或感知抗癌益处.
- 荷兰初级脑瘤患者中的大麻使用模式和动机尚不清楚.
- 这项研究调查了大麻使用的流行程度,类型,动机,感知效应和这一群体的不良事件.
研究的目的:
- 确定原发性脑瘤患者以前和现在使用大麻的流行率.
- 确定患者使用大麻的动机,包括缓解症状和假定的抗瘤作用.
- 在这个队列中记录与大麻使用相关的感知治疗效果和不良事件.
主要方法:
- 在成年原发性脑瘤患者中进行了横截面调查.
- 从访问阿姆斯特丹UMC神经瘤门诊的患者收集了数据.
- 该调查于2023年8月至10月期间进行.
主要成果:
- 在100名受访患者中,51%曾经使用过大麻;14%目前使用它.
- 19%的人因与瘤相关的原因使用大麻,主要是缓解症状 (74%) 和假定的抗瘤作用 (42%).
- 患者更喜欢大麻二醇 (CBD) 而不是四大麻二醇 (THC);常见的好处包括改善睡眠,焦虑和情绪,以嗜睡和口腔干燥为频繁的不良事件.
结论:
- 很大一部分原发性脑瘤患者使用大麻,通常用于症状管理和潜在的抗瘤作用.
- 观察到的使用率表明需要对大麻治疗疗效进行临床研究,以控制症状和抗瘤特性.
- 需要进一步调查睡眠障碍,抑郁症状,焦虑和瘤抑制能力.
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