在甲状腺功能低下症患者中,对睡眠质量和定量变量进行多睡眠评估
Manogna Ghantasala1, Nitin A John1, Madhuri Taranikanti1
1Department of Physiology, All India Institute of Medical Sciences, Bibinagar, Telangana, India.
Journal of family medicine and primary care
|August 15, 2025
概括
甲状腺功能低下症显著扰乱睡眠质量,导致白天睡眠增加和像阻塞性睡眠呼吸暂停 (OSA) 这样的情况. 在高危患者中早期评估OSA对于改善他们的生活质量至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
- 肺部病理学 肺部病理学
背景情况:
- 甲状腺功能低下症经常与睡眠质量不佳有关,表现为失眠,白天嗜睡,打和呼吸困难.
- 在甲状腺功能低下症患者中,睡眠障碍的严重程度各不相同.
研究的目的:
- 评估和比较临床和亚临床甲状腺功能低下症患者的睡眠质量和定量睡眠变量.
主要方法:
- 一项涉及30名未接受治疗的临床或亚临床甲状腺功能低下症患者 (30-50岁) 的横截面研究.
- 使用爱普沃思睡眠度量 (ESS) 评估睡眠质量,并通过多睡眠学 (PSG) 测量客观睡眠参数.
- 激素水平 (TSH,tT3,tT4) 用化学发光免疫测试 (CLIA) 来测量.
主要成果:
- 与亚临床病例相比,临床甲状腺功能低下症患者的ESS得分显著提高,睡眠效率降低,睡眠阶段持续时间改变.
- 在甲状腺功能低下患者中观察到呼吸暂停-低呼吸指数 (AHI) 和氧气不和指数 (ODI) 的增加,临床甲状腺功能低下患者的AHI较高.
- 观察到高兴度和打指数,特别明显在临床甲状腺功能低下症患者中.
结论:
- 阻塞性睡眠呼吸暂停 (OSA) 是甲状腺功能低下症的一个未被确诊的并发症.
- 患有风险因素,大声打和过度白天嗜睡的患者应接受OSA查.
- 诊断和管理OSA可以显著提高甲状腺功能低下患者的生活质量.
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