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Updated: Sep 11, 2025

Establishing a High Throughput Epidermal Spheroid Culture System to Model Keratinocyte Stem Cell Plasticity
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Establishing a High Throughput Epidermal Spheroid Culture System to Model Keratinocyte Stem Cell Plasticity

Published on: January 30, 2021

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毛囊球形的发育,具有生长因子转染和各种细胞组合

Hyeon-Min Nam1,2, Subin Jeong1,2, Gun Yong Sung1,2,3

  • 1Interdisciplinary Program of Nano-Medical Device Engineering, Hallym, University, Chuncheon 24252, Republic of Korea. gysung@hallym.ac.kr.

Biomaterials science
|August 15, 2025
PubMed
概括

研究人员开发了一种新的毛囊模型,使用基因转移细胞来研究头发生长. 这种先进的皮肤模型显示了新的脱发治疗和皮肤病学研究的潜力.

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Gene Transfection toward Spheroid Cells on Micropatterned Culture Plates for Genetically-modified Cell Transplantation

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Mammary Epithelial and Endothelial Cell Spheroids as a Potential Functional In vitro Model for Breast Cancer Research08:30

Mammary Epithelial and Endothelial Cell Spheroids as a Potential Functional In vitro Model for Breast Cancer Research

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Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
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