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Updated: Sep 11, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Published on: March 15, 2024

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m6A 修饰-CYP1B1 通过抑制铁灭促进HCC细胞增殖

Wenwen Huang1, Haihong Hu1, Sheng Cai1

  • 1Institute of Drug Metabolism and Pharmaceutical Analysis, National Key Laboratory of Advanced Drug Delivery and Release Systems, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Cancer Center, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.

Current drug metabolism
|August 15, 2025
PubMed
概括

细胞染色体P450家族1亚家族B成员1 (CYP1B1) 通过抑制铁亡,促进肝细胞癌 (HCC) 细胞增殖. 由METTL14介导的m6A修饰会负面调节CYP1B1,为HC.CC提供潜在的治疗标.

关键词:
在CYP1B1B1中.在HCC中,HCC是HCC.药物代谢的药物代谢.铁性化 (ferroptosis) 是一种m6A 一个很好的.机械设备. 机械设备. 机械设备.

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