暴露前预防 两家联邦合格卫生中心的处方差异
Eleanor E Friedman1, Joseph A Mason1, Samantha A Devlin1
1Section of Infectious Diseases and Global Health, Department of Medicine, University of Chicago, Chicago, IL 60637, USA.
Sexually transmitted diseases
|August 15, 2025
概括
暴露前预防 (PrEP) 用于预防艾滋病毒显示差异. 白人男性最常接受PrEP处方,而女性每次性传播感染 (STI) 诊断的处方显著减少.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 预防艾滋病毒 预防艾滋病毒
背景情况:
- 暴露前预防 (PrEP) 对于预防艾滋病毒至关重要,但面临不平等的吸收.
- 这项研究调查了人口群体在PrEP使用中的差异.
研究的目的:
- 为了在不同性别,种族和族群中比较性传播感染 (STIs) 和PrEP处方.
- 在联邦合格卫生中心 (FQHC) 识别和量化PrEP处方差异.
主要方法:
- 从1/1/2023年到12/31/2023.电子医疗记录的回顾性分析.
- 识别性传播感染诊断 (淋病,克拉米迪亚,梅毒) 和PrEP启动处方.
- 计算PrEP启动率,与白人男性相比的速度差异,以及不同人口群体的PrEP启动与性传播疾病诊断比率.
主要成果:
- 在63,591名患者中,1.9%患有性病,0.1%开始接受PrEP.
- 西班牙裔男性,黑人女性,白人女性和西班牙裔女性与白人男性相比显示PrEP差异.
- 在白人男性中,PrEP启动与性传播疾病诊断的比例最高 (0.42),在所有其他群体中,尤其是女性中,比例明显较低.
结论:
- 白人男性的初始PrEP处方率最高.
- 男人接受PrEP的频率比女性高3到21倍,这突显了艾滋病毒预防获取的性别差异.
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