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Updated: Sep 11, 2025

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis
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对AMT复合物的基质结合的结构洞察力,通过抑制剂被困状态

Zengyu Shao1, Sol Yoon1, Jiuwei Lu1

  • 1Department of Biochemistry, University of California, Riverside, California, USA.

Protein science : a publication of the Protein Society
|August 15, 2025
PubMed
概括

与DNA模仿物结合的Tetrahymena thermophila AMT复合物的结构揭示了它的组装机制. 这一发现为N6-氨酸DNA甲基化调节和基因组稳定提供了洞察力.

关键词:
6mA的DNA甲基化一个复杂的AMT综合体.在DNA甲基转移酶中.酶基质的识别.家庭 家庭域名 家庭域名维护DNA甲基化 维护DNA甲基化开放到关闭的形状转变.蛋白DNA相互作用

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