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Updated: Sep 11, 2025

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多双 (PCB) 在体内与药物代谢相互作用

Julian Peter Müller1, Jens Rengelshausen2, Salah Laieb2

  • 1Institute of Clinical Pharmacology, University Hospital of RWTH, 52074, Aachen, Germany.

Archives of toxicology
|August 15, 2025
PubMed
概括

多双 (PCB) 通过影响细胞P450 (CYP) 酶来改变药物代谢. 这项研究表明,PCB可以急剧改变药物的疗效和安全性,需要将其纳入药理动力学模型.

关键词:
在CYP1A2/CYP2C9酶调节过程中.细胞染色体P450的使用.药物代谢药物代谢环境毒理学环境毒理学多双 (PCB) 是一种多化合物.

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