社交时差和阻塞性睡眠呼吸暂停的严重程度:基于多睡眠图的回顾性研究
Shuai Wu1, MaoHuan Peng1, YuHua Zuo1
1Division of Sleep Medicine, Peking University People's Hospital, Beijing, China.
Sleep medicine
|August 15, 2025
概括
严重的社交时差,睡眠时间表的不匹配,显着加剧了阻塞性睡眠呼吸暂停 (OSA) 的严重程度,由更高的呼吸暂停-呼吸暂停指数 (AHI) 表示. 这种效应部分是由于白天的嗜睡,在男性和吸烟者中更为明显.
科学领域:
- 睡眠医学 睡眠医学
- 时间生物学 时间生物学
- 公共卫生 公共卫生
背景情况:
- 社会时差,即生物和社会睡眠时间之间的差异,与健康状况不佳有关.
- 社交时差和阻塞性睡眠呼吸暂停 (OSA) 严重程度之间的关系尚不清楚.
研究的目的:
- 调查社交时差和阻塞性睡眠呼吸暂停 (OSA) 严重程度之间的关联,用呼吸暂停-呼吸暂停指数 (AHI) 来衡量.
- 探索白天嗜睡的调解作用,以及由人口统计和临床因素对效果的改变.
主要方法:
- 对2383名OSA患者进行过多睡眠学术的回顾性分析.
- 社会时差量化为工作和休息日 (最小,中等,严重) 之间的午睡差异.
- 多重线性回归和调解分析,具有子组和通用添加模型 (GAM).
主要成果:
- 严重的社会时差独立地与更高的AHI相关 (p=0.004).
- 爱普沃思睡眠度量 (ESS) 中介于社会时差-AHI协会的19.4%.
- 在男性和吸烟者中观察到更强的关联;非线性增加的AHI与社会时差.
结论:
- 严重的社交时差独立地提高了OSA患者的AHI,部分是由白天嗜睡的介导.
- 循环失调成为影响OSA严重程度的潜在可修改因素.
- 调查结果强调了解决OSA管理中的社会时差的重要性,特别是在男性和吸烟者中.
相关概念视频
Sleep Apnea
220
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
220
Substance Use Disorders Affecting Sleep
217
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
217
Insufficient Sleep and Sleep Deprivation
210
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
210
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.6K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.6K
REM Sleep Behavior Disorder
405
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
405
Sleep-Wake Cycles
1.6K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.6K


