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Updated: Sep 11, 2025

Antibiotic Dereplication Using the Antibiotic Resistance Platform
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Published on: October 17, 2019

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对新型抗生素设计的生成深度学习方法

Aarti Krishnan1, Melis N Anahtar2, Jacqueline A Valeri3

  • 1Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Institute for Medical Engineering & Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.

Cell
|August 15, 2025
PubMed
概括

这项研究引入了一个新的AI框架来设计新的抗生素. 产生性人工智能成功地制造并合成了具有强大抗菌活性的化合物来对抗抗菌.

关键词:
尼塞利亚淋病黄金葡萄球菌抗生素细菌感染新的设计药物发现一些碎片生成型的人工智能图形神经网络机器学习

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