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Omar Nasher¹, Colton D Wayne¹, Ruiqi Cen²

¹Department of Pediatric Surgery, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA.

Journal of pediatric surgery

|August 15, 2025

概括

较低的社会经济地位 (SES) 是婴儿死性肠球炎 (NEC) 的重要危险因素,独立于早产. 针对低SES家庭的有针对性的干预措施可以减少这种严重的婴儿疾病的负担.

科学领域:

新生儿研究新生儿研究
儿科健康结果的结果.
健康的社会经济决定因素

背景情况:

死性肠球炎 (NEC) 是一种严重的胃肠道疾病,会影响早产婴儿.
过早生育,通常与较低的社会经济地位 (SES) 相关,是NEC的已知风险因素.
对于SES对NEC发展或严重性的独立贡献仍然不清楚.

研究的目的:

调查社会经济地位 (SES) 与婴儿死性肠球炎 (NEC) 风险之间的独立关联.
确定早产是否调解了SES和NEC之间的关系.
探索SES对NEC严重性和手术干预的必要性的影响.

主要方法:

利用儿科健康信息系统 (PHIS) 数据库 (2016-2023) 来识别患有NEC的婴儿.
匹配的NEC病例 (n=11,181) 与基于妊娠年龄,时间年龄,种族/种族和心脏病的非NEC对照.
使用多变量后勤回归和调解分析,使用家庭收入中位数 (MHI) 和儿童机会指数 (COI) 来衡量SES.

主要成果:

患有NEC的婴儿显著更有可能来自较低的SES地区 (较低的MHI和COI;p < 0.0001).
较低的MHI和COI在调整了混因素后,独立地与增加的NEC风险有关.
过早生育仅占SES和NEC之间的约27-29%的关联,这表明SES有直接的影响.
在SES指标和NEC患者手术干预的需要之间没有发现一致的关联.

结论:

较低的社会经济地位 (SES) 是发展死性肠球炎 (NEC) 的独立风险因素.
SES和NEC之间的联系超出了早产的影响.
针对低SES家庭的干预措施可能对减少NEC的整体负担至关重要.

关键词:

这就是COI COI.儿童机会指数儿童机会指数 MHIHI MHIHI 的意思是什么家庭收入的中位数.NEC NEC NEC是指一个国家.死性肠道结肠炎的发生.健康的社会决定因素社会经济地位社会经济地位

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