下调的AhR表达与增加的IFN-γ生产和在白病中受损的免疫检查点上调相关 (MS# JID-2024-1072)

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Updated: Sep 11, 2025

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
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Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Published on: September 20, 2017

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Arno Belpaire1, Annelies Demeyer2, Danique Berrevoet3

  • 1Department of Dermatology, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium; Head and Skin Research Group, Ghent University, UFO-building, Campus Ufo, Sint-Pietersnieuwstraat 33, 9000 Ghent, Belgium.

The Journal of investigative dermatology
|August 15, 2025
PubMed
概括

在白风中, kynurenine-aryl-hydrocarbon-receptor (AhR) 通路被破坏,导致T细胞活性增加. 用AhR激动剂向这种途径可能会恢复免疫平衡并治疗白风.

关键词:
阿里尔碳化合物受体的使用IFN-γ 信号传输系统免疫检查站 免疫检查站基努瑞宁路径的通道.脊髓灰质炎 (Vitiligo) 是一种疾病.

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