睡眠时间和心血管疾病之间的关系:基于Charls的前性队列研究
Yong He1, Hongkun Wu1, Yongjin Luo1
1Chongqing general hospital, Chongqing university.
The American journal of cardiology
|August 15, 2025
概括
睡眠时间短 (<5小时) 与中国老年人心血管疾病 (CVD) 风险较高有关. 睡眠6-8小时与最低的心血管疾病风险相关,强调睡眠.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 睡眠科学 睡眠科学
背景情况:
- 对睡眠障碍与慢性疾病之间的联系越来越感兴趣.
- 在中国,关于睡眠时间与心血管疾病 (CVD) 的纵向关系的国家数据稀缺.
- 由于中国成年人心血管疾病负担较高和区域健康差异,需要进行调查.
研究的目的:
- 研究45岁以上中国成年人睡眠时间和心血管疾病之间的动态关系.
- 评估睡眠-心血管疾病风险中的非线性关联和子组异质性.
- 利用来自中国健康与退休长度研究 (CHARLS) 的多个数据波.
主要方法:
- 使用3波查尔斯数据的前性队列研究 (2011年,2013年,2015年).
- 多变量逻辑回归和受限立方线 (RCS) 模型用于关联分析.
- 为人口统计,生活方式和并发症进行调整;进行子组分析.
主要成果:
- 睡眠时间短 (<5小时) 显著与心血管疾病风险增加有关.
- 最佳睡眠时间 (6-8小时) 与心血管疾病风险最低相关.
- 每增加一小时的睡眠,心血管疾病的几率降低了约9%;在老年人,受过高等教育者和非吸烟者中,保护作用更强.
结论:
- 强有力的纵向证据表明,中老年/老年中国成年人睡眠时间和心血管疾病风险之间存在反向关系.
- 睡眠时间<5小时与心血管疾病风险增加相关;6-8小时与最低风险相关.
- 强调将睡眠健康纳入心血管疾病预防策略.
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