在墨西哥跨性别女性中使用暴露前预防的意愿:潜伏阶级分析
Heleen Vermandere1, Santiago Aguilera-Mijares1, Joaquín Escobar Trinidad1
1Center for Evaluation Research and Surveys, National Institute of Public Health of Mexico, Cuernavaca, Mexico.
International journal of STD & AIDS
|August 15, 2025
概括
墨西哥大多数跨性别女性愿意使用艾滋病毒暴露前预防 (PrEP),但意识仍然很低. 需要量身定制的策略,以增加跨性别女性特定子组的PrEP吸收率.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 社会科学 社会科学 社会科学
背景情况:
- 在墨西哥的跨性别女性中存在高艾滋病毒患病率.
- 在这个人群中,与艾滋病毒暴露前预防 (PrEP) 的接触是不理想的.
- 了解使用PrEP的意愿及其与风险行为之间的关系对于有针对性的干预至关重要.
研究的目的:
- 评估墨西哥跨性别女性是否愿意使用艾滋病毒暴露前预防 (PrEP).
- 检查艾滋病毒风险行为与使用PrEP的意愿之间的关联.
- 根据风险行为和PrEP意愿,确定跨性别女性的子组.
主要方法:
- 2021年在墨西哥的266名跨性别女性中进行了一项横截面研究.
- 隐性类分析 (LCA) 用于识别不同的风险行为概况.
- 使用多变量逻辑回归来确定与PrEP意愿相关的因素.
主要成果:
- 只有40%的参与者知道PrEP,但78%的人表示愿意在引入后使用它.
- 确定了三个不同的风险行为类别:较低风险的交易性 (10%),较高风险的无交易性 (25%) 和较高风险的交易性 (65%).
- 使用PrEP的意愿在高风险的交易性群体 (85%) 中最高,并与属于此类 (aOR:3.3) 相关.
结论:
- 使用PrEP的意愿通常与感知到的艾滋病毒风险保持一致,特别是在高风险群体中.
- 一个显著的子组 (第二类) 呈现出更高的风险行为,但更低的意愿使用PrEP,表明吸收的潜在差距.
- 干预策略必须量身定制,以满足不同跨性别女性子组的特定需求和意识水平,以改善PrEP参与度.
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