免疫检查点抑制剂的实际使用模式,基于韩国国家健康保险服务数据
Eunji Kim1, Yu-Seon Jung2, Jongmin Lee1
1College of Pharmacy, Chung-Ang University, Seoul, Republic of Korea; Department of Global Innovative Drugs, the Graduate School of Chung-Ang University, Seoul, Republic of Korea.
Clinical therapeutics
|August 15, 2025
概括
韩国免疫检查点抑制剂 (ICI) 的使用从2017年至2022年急剧增加,肺癌,尿路癌和肝癌最常治疗. 与其他疗法的结合也增加了,扩大了先进癌症治疗选择.
科学领域:
- 在瘤学瘤学.
- 免疫疗法是一种免疫疗法.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 免疫检查点抑制剂 (ICI) 代表了癌症治疗的重大进展.
- 了解现实世界的利用模式对于优化癌症护理策略至关重要.
研究的目的:
- 在韩国全面分析免疫检查点抑制剂 (ICI) 的利用模式.
- 研究ICI与传统抗癌疗法的组合.
主要方法:
- 对2017年至2022年韩国索赔数据的回顾性分析.
- 包括接受至少一剂ICI的癌症患者.
- 描述性统计数据,以确定ICI使用趋势,按年,癌症类型和组合治疗.
主要成果:
- 在2017年至2022年期间,超过41,000名患者接受了ICI,每年使用量显著增加.
- 肺癌 (66.6%) 是最常见的征兆,其次是泌尿道癌 (11.3%) 和肝/胆道癌 (10.6%).
- 2020年至2022年间,肝/胆道癌症的ICI使用量显著增加,自2020年以来,结合疗法使用量增加.
结论:
- 韩国的ICI患者使用率显示出持续的上升趋势.
- 扩大监管批准已经扩大了ICI指示.
- 越来越多地使用组合疗法反映了晚期癌症的增强治疗选择.
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