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Updated: Sep 11, 2025

Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue
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Published on: November 30, 2018

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CoREST3在阿尔茨海默病和HDAC2调节中表现出异型特异性表达

Simon Maksour1,2, Helena Targa Dias Anastacio3, Jeremy S Lum3

  • 1School of Medical, Indigenous and Health Science and Molecular Horizons, University of Wollongong, Northfields Avenue, Wollongong, NSW, 2522, Australia. smaksour@uow.edu.au.

BMC biology
|August 15, 2025
PubMed
概括

REST核心压缩剂3 (CoREST3) 直接以异构体特异的方式调节氨酸脱乙酶2 (HDAC2). 在阿尔茨海默病 (AD) 中失调的CoREST3大脑可能会改变HDAC2水平,从而导致AD的发病.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.这就是COREST3的原因.在 HDAC2 中,HDAC2 是在IPSC中,您可以使用IPSC.这些神经元是神经元.在RCOR3中使用RCOR3.

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