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探索一种创新的酵母结合铁补充剂的耐受性和副作用:一个可行性试验

Keely A Shaw^1,2,3,4, Thomas A Tompkins⁵, Brendan Abrahamson-Durant⁶

¹Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada. keely.shaw@ucalgary.ca.

Pilot and feasibility studies

|August 15, 2025

概括

铁酵母复合体 (FeSC) 饼干被女运动员容忍得很好,显示了未来铁状况试验的可行性. 这种新的铁输送方法可以改善粘附性并减少胃肠道问题.

科学领域:

运动医学运动医学
营养科学营养科学
胃肠病学胃肠病学

背景情况:

铁缺乏症在女性运动员中很常见,导致疲劳和性能降低.
口服铁补充剂通常会引起胃肠道副作用,导致粘附性差.
铁酵母复合物 (FeSC) 被研究为一种潜在的更好耐受的替代品.

研究的目的:

评估铁酵母复合体 (FeSC) 补充剂在活跃女性中的可行性和耐受性.
评估FeSC补充剂对胃肠道的影响和可接受性.
为了确定FeSC是否适合进一步的临床试验.

主要方法:

一个单臂混合方法可行性试验,涉及14名活跃女性 (18-25岁).
参与者在14天内每隔一天食用FeSC强化饼干 (40毫克元素铁).
通过验证的问卷进行了胃肠道症状,压力和恢复的监测;可接受性被定性评估.

主要成果:

符合所有可行性标准,100%的保留,遵守和填写问卷.
参与者报告了良好的耐受性和轻微的,短暂的胃肠道症状.
观察到便秘和腹症状的减少; 57%的人更喜欢饼干而不是药丸.

结论:

用饼干形式补充FeSC是可行的,并且在活跃的女性中耐受良好.
该补充剂显示了潜在的胃肠道益处和良好的可接受性.
这些发现支持进行更大规模的试验,以评估FeSC对铁状况和长期坚持的影响.

关键词:

胃肠道症状胃肠道症状铁缺乏症铁缺乏症营养酵母是一种营养酵母.补充合规性补充合规性

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