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Updated: Sep 11, 2025
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视网膜母细胞瘤生物标志物的全球研究格局:基于多个数据库 (2005-2025) 的多学科文献识别分析 (2005-2025)
Zhixin Peng1,2, Qi Hu1,3, Xiangdong Chen4
1The First Clinical Chinese Medicine College of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Journal of cancer research and clinical oncology
|August 15, 2025
概括
这项研究分析了对视网膜母细胞瘤 (RB) 生物标志物的研究,揭示了液体活检和AI集成等关键趋势. 生物标志物对于个性化RB治疗和未来研究重点至关重要.
科学领域:
- 在瘤学瘤学.
- 生物标志物发现发现
- 眼科医生 眼科 眼科
背景情况:
- 视网母细胞瘤 (RB) 诊断研究存在,但缺乏对生物标志物影响的系统定量分析.
- 了解RB生物标志物的研究环境对于推进诊断和治疗至关重要.
研究的目的:
- 从2005年到2025年,系统地分析研究环境,并确定视网膜母细胞瘤 (RB) 生物标志物的热点.
- 为未来对RB生物标志物的研究提供理论参考.
主要方法:
- 从科学网络和Scopus (2005-2025) 的出版物中获取了这些出版物.
- 通过使用R软件,VOSviewer和CiteSpace.Space进行了图书统计分析.
主要成果:
- 出版产量稳步增长,从2013年至2021年间的增长加速. 中国在数量上领先,美国在合作方面领先.
- 关键的研究热点包括液体活检,瘤异质性,向治疗,免疫逃避和AI集成.
- RB生物标志物研究的重点是反映瘤负担,调节瘤基因,驱动EMT,调解免疫逃避,以及基于AI的异质性识别.
结论:
- 生物标志物正在成为视网膜母细胞瘤 (RB) 个性化治疗优化的关键工具.
- 全球对RB生物标志物的研究关注度很大,预计将加强.
- 这项研究为当前的研究环境和RB生物标志物研究的未来方向提供了宝贵的见解.
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