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Updated: Sep 11, 2025

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
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cGAS-STING通路调制:神经再生的新希望

Jinghan Zhang1, Mouyuan Sun2, Yaxian Luo2

  • 1Department of Orthopedics, the First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.

Neural regeneration research
|August 16, 2025
PubMed
概括

针对cGAS-STING通路显示神经疾病中神经再生的希望. 抑制这种途径可能会增强神经修复的恢复和组织工程方法.

关键词:
生物材料是一种生物材料.cGAS-STING 的使用情况.神经损伤的神经损伤神经再生的神经再生神经退行症的神经退行症神经炎症是一种神经炎症.精准医学是一门精准医学.组织工程是组织工程.

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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