一项关于临床参数和经过试管婴儿治疗的夫妇心理之间的可能相互作用的试点调查
Gercek Aydin1,2, Mehmet Bulbul3, Elif Ergin1
1Bursa Eurofertil IVF Center, Bursa, Turkey.
概括
焦虑和抑郁不会显著影响体外受精 (IVF) 怀孕率. 然而,女性的严重焦虑和男性的高焦虑与受精和胚胎发育的减少相关,可能会降低累积成功.
科学领域:
- 生殖医学 生殖医学
- 心理医学 心理医学
- 不孕症研究 不孕症研究
背景情况:
- 在接受体外受精 (IVF) 的患者中,心理困扰是常见的.
- 患者心理状态与试管婴儿结果之间的相互关系需要进一步研究.
研究的目的:
- 探索试管婴儿治疗和患者的心理健康之间的双向影响.
- 评估焦虑和抑郁对IVF关键参数和怀孕率的影响.
主要方法:
- 一项针对180对接受试管婴儿治疗的夫妇的前性队列研究.
- 在药物治疗前和胚胎移植后,对焦虑和抑郁症进行贝克库存的管理.
- 基于高质量的胚胎细胞发育的怀孕结果分析,不包括分裂阶段的转移.
主要成果:
- 基于焦虑或抑郁的增加,没有观察到怀孕率的显著差异.
- 在试管婴儿前的妇女中,严重的焦虑与受精率的降低以及较低的母细胞/卵细胞和母细胞/M2比率相关.
- 男性的高焦虑 (在试管婴儿前或后) 与卵细胞数量,M2,受精,胚胎细胞和胚胎总数的减少有关.
结论:
- 焦虑和抑郁不会显著影响胚胎细胞植入成功或整体怀孕率.
- 严重的焦虑会降低受精率,导致更少的胚胎和胚胎,可能会影响累积妊娠率.
- 虽然没有直接影响植入,但心理因素需要注意,因为它们对早期试管婴儿参数的影响.
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