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Updated: May 22, 2026

Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells
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单细胞转录组分析揭示了胰腺神经内分泌瘤中转移相关的PCSK1+神经内分泌亚群

Xiaolei Yin1, Xiaopeng Li2, Lili Mi1

  • 1Department of Gastroenterology, Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

Journal of neuroendocrinology
|August 16, 2025
PubMed
概括

胰腺神经内分泌瘤 (PNETs) 通过不同的神经内分泌细胞亚群发展. 一个转移丰富的PCSK1+亚群从NEUROD1+细胞中产生,由ATF6调节并受到纤维细胞信号的影响.

关键词:
在PCSK1+亚种群中.肝脏转移的发生.神经内分泌子群的部分.胰腺神经内分泌瘤一个单细胞RNA测序.

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