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Updated: May 3, 2026

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倾斜平衡:PD1轴作为慢性炎症性脱髓化多神经病的调节器

Melissa Sgodzai1,2, Katharina Klöster1, Hilal Karakaya1,2

  • 1Department of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44801, Bochum, Germany.

Brain : a journal of neurology
|August 16, 2025
PubMed
概括

周围神经系统的免疫耐受性依赖于PD1轴的活动,这对于预防慢性炎症性脱髓化多神经病症等自身免疫性疾病至关重要. 这项研究揭示了PD1轴在小鼠模型和人类患者中的参与,突出了其在免疫检查点网络中的作用.

关键词:
慢性炎症性脱髓化多神经病变 (CIDP)免疫调节 免疫调节免疫耐受性 免疫耐受性免疫检查点的检查点周围神经系统 周围神经系统

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