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通过深度学习和AlphaFold 3设计功能调节RNA

Yan Xia1,2, Zeyu Liang1, Xiaowen Du1

  • 1Department of Gastroenterology, Aerospace Center Hospital, College of Life Science, Beijing Institute of Technology, No. 5 South Zhongguancun Street, Haidian District, Beijing, Beijing Municipality 100081, China.

Briefings in bioinformatics
|August 16, 2025
PubMed
概括

本研究介绍了一个计算框架,用于设计使用深度学习和基于能源的方法的多样化和高效的单导向RNA (sgRNA). 设计的sgRNA实现了高基因编辑效率,展示了RNA设计的新策略.

关键词:
阿尔法Fold3是什么意思克里斯普尔是什么意思?克里斯普尔是什么意思?设计RNA设计RNA设计深度学习是一种深度学习.基因编辑 基因编辑

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