认知障碍与动脉置换术的利用和急性结果的关联
Konmal Ali1, Amulya Vadlakonda1, Sara Sakowitz1
1Cardiovascular Outcomes Research Laboratories (CORELAB), Department of Surgery, University of California, Los Angeles, CA.
Surgery
|August 16, 2025
概括
在接受大动脉置换的老年人中,认知障碍与更高的并发症率和成本有关. 这凸显了针对性干预的必要性,以改善这些患者的治疗结果.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 神经科学是一个神经科学.
背景情况:
- 严重的大动脉狭窄症越来越多地在老年人中被诊断出,需要进行诸如手术或透气管大动脉置换等干预措施.
- 认知障碍影响高达30%的老年患者,可能会影响手术结果.
研究的目的:
- 检查在接受大动脉置换的老年人中术前认知障碍和术后结果之间的独立关联.
主要方法:
- 对2016-2021年全国再接收数据库的分析,针对65岁以上接受外科手术或透气管大动脉置换的患者.
- 根据手术前认知障碍或痴呆症的存在或不存在,对患者进行分层分类.
- 使用多变量回归模型来评估认知障碍对各种临床和财务结果的影响.
主要成果:
- 在505,356名患者中,大约3.3%的患者患有认知障碍,这组患者年龄较大,更有可能接受过导管大动脉置换.
- 认知障碍与心脏,呼吸道和传染性并发症的几率增加有关,无论是跨导管大动脉置换组还是外科大动脉置换组.
- 认知障碍患者经历了更高的住院费用,非家庭出院率的增加,以及更大的30天非选择性再入院.
结论:
- 手术前的认知障碍与接受过导管大动脉置换的可能性更高有关,但导致临床和财务结果较差.
- 需要进一步的研究,以确定导致这一群体患病率增加的因素.
- 开发量身定制的医院内外干预措施对于改善接受主动脉置换的认知障碍老年人护理至关重要.
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