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Updated: Jul 12, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
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针对前带带皮层抑制的优化深度大脑刺激在小鼠中产生了类似抗抑郁药的效果

Zhengwei Yuan1, Haonan Yang2, Peng Wang1

  • 1Beijing Institute for Brain Research, Peking Union Medical Collage and Chinese Academy of Medical Sciences, Beijing 102206, China; Chinese Institute for Brain Research, Beijing 102206, China.

Neuron
|August 16, 2025
PubMed
概括

深度大脑刺激 (DBS) 在重大抑郁障碍 (MDD) 方面显示出有前途. 优化前带带皮层 (ACC) 的DBS参数显示,抑制ACC活动产生抗抑郁作用.

关键词:
优化 DBS 的优化.这是一个无情的世界,无情的世界.前带状皮层前带状皮层深度大脑刺激 刺激大脑抑郁 抑郁症 抑郁症 抑郁症 抑郁症纤维光度仪的光度仪.大型抑郁症主要是抑郁症.神经电路的神经电路.通过神经调节进行神经调节.在pPDH的基础上,pPDH是

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Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...