心力衰竭和心房的人的死亡率趋势:基于人口的队列研究
Nicholas R Jones1, Margaret Smith2, Yaling Yang1
1Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
The lancet. Healthy longevity
|August 16, 2025
概括
并发性心力衰竭和心房动显著增加死亡风险. 随着时间的推移,生存率并没有得到改善,在社会贫困人口中观察到的最差的结果.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 心房动 (AF) 和心力衰竭 (HF) 经常同时存在,但它们对生存的综合影响尚未完全理解.
- 需要对AF和HF患者的当代死亡率估计和趋势进行研究.
研究的目的:
- 估计心房动和心力衰竭患者当代死亡率.
- 分析被诊断为AF和HF的患者随着时间的推移死亡率的趋势.
主要方法:
- 使用英语初级和中等保健数据 (2000-2018年) 进行的回顾性队列研究.
- 包括45岁或以上的成年人,有事件或先前存在的AF和/或HF.
- 分析所有原因死亡率,中位数存活率和累积死亡率概率,按诊断状态,时间,性别,年龄和社会经济贫困分层.
主要成果:
- 该队列包括超过230万人;在研究结束时,有74470人患有AF和HF.
- 患有这两种疾病的患者的存活率明显较低 (平均3.15年),相比只有一种疾病的患者.
- 同病性AF和HF的死亡率没有随着时间的推移而有所改善,并且在最贫困的五分位数中明显恶化 (平均存活时间为2.67年).
结论:
- 并发性心力衰竭和心房动是常见的,并与预后不佳有关.
- 随着时间的推移,这些诊断的死亡率没有改善.
- 社会上处于贫困的群体经历了最糟糕的生存结果.
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