在ESD后以内镜图像为基础预测食道狭窄,使用粘膜缺陷指标
Wei Lin1,2, Yi-Zhi Liang3, Dun-Huang Peng3
1Department of Endoscopy Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Annals of surgical oncology
|August 16, 2025
概括
在食道内镜下粘膜解剖 (ESD) 后量化粘膜缺陷的大小可以预测狭窄风险. 切除区域和周围的图像分析提供了一种可靠的方法来评估ESD后狭窄的发展.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 医疗成像医学成像
背景情况:
- 食道狭窄是内镜下粘膜切割 (ESD) 后的一个显著并发症.
- 目前在ESD后预测狭窄的标准不是定量性的.
- 确定ESD后食道狭窄的预测因素至关重要.
研究的目的:
- 为了确定ESD后食道狭窄的预测因素.
- 探索用于预测术后狭窄的定量指标.
- 开发一种预测模型,用于ESD后食道狭窄.
主要方法:
- 对经过食道ESD的患者内镜数据的回顾性分析.
- 使用Image Pro Plus 6.0.0测量切除的粘膜缺陷区域和周围.
- 后勤回归,ROC曲线分析和名ogram模型构建用于预测.
主要成果:
- 中间缺陷面积:527.74mm2,中间周长:91.75mm,中间周长比为33%.
- 缺陷面积,周长和周长比是狭窄症的独立风险因素 (P < 0.05).
- 预测模型显示出良好的内部验证 (C统计:0.747-0.875).
结论:
- 切除的粘膜缺陷区域和周边的定量分析准确地预测ESD后食道狭窄.
- 图像分析技术为评估狭窄风险提供了可靠的工具.
- 这种量化有助于管理患有食道ESD的患者.
相关概念视频
Endoscopic Procedures I: Esophagogastroduodenoscopy
350
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
350
Esophageal Strictures-I: Introduction
267
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
267
Esophageal Strictures-II: Clinical Features and Management
157
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
157
Barrett Esophagus-I: Introduction
201
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
201


