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Updated: Sep 11, 2025

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
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致癌形式和BRCA致病变体乳腺癌的特征

Takaaki Fujii1

  • 1Department of Breast Surgery and Oncology, Nippon Medical School Chiba Hokusoh Hospital, 1715 Kamagari, Inzai, Chiba, 270-1694, Japan. ftakaaki@gunma-u.ac.jp.

International journal of clinical oncology
|August 17, 2025
PubMed
概括

在BRCA1和BRCA2基因的生殖基因突变导致遗传性乳腺和卵巢癌 (HBOC) 综合征. 对BRCA致病变体 (PVs) 的基因检测对于个性化癌症治疗和降低风险至关重要.

关键词:
这就是BRCA BRCA.乳腺癌 乳腺癌 乳腺癌致癌的发生是致癌的产生.雌激素是一种雌激素.在 HBOC HBOC HBOC人力资源副主任HRD

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