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A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
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在减压过程中长时间吸入氧气的高压空气暴露对潜水员心血管功能的影响
Liu Wenwu1, Zhang Tingting1, Yin Lijun2
1Department of Diving and Hyperbaric Medicine, Naval Medical Center, Naval Medical University, Shanghai, 200433, China.
概括
在高压空气暴露后,在减压过程中长时间吸入氧气会轻微影响潜水员的心血管功能,影响血压和动脉流动. 心率和心率输出也显示显著减少.
科学领域:
- 心血管生理学心血管生理学
- 潜水医学是一门潜水医学.
- 高压生理学 高压生理学
背景情况:
- 潜水员在高压暴露和减压期间经历了显著的生理压力.
- 了解呼吸气体混合物的心血管影响,包括氧气,在减压过程中对于潜水员安全至关重要.
研究的目的:
- 调查在水族中减压过程中长时间吸入氧气对心血管的影响.
- 评估高压空气暴露后心脏,动脉和臂动脉功能的变化.
主要方法:
- 八名潜水员在400kPa的高压空气中暴露.
- 在减压过程中氧气呼吸的持续时间在不同的深度上有所不同.
- 用超声波测量,在暴露前和暴露后测量心血管参数.
主要成果:
- 观察到透气血压显著增加,心率显著下降.
- 常见的动脉峰值的缩和终端的舒张速度下降,而手臂动脉直径倾向于增加.
- 心脏输出,E波和A波显著减少,肺动脉流速下降的趋势.
结论:
- 400kPa的高压空气暴露与减压期间长时间的氧气吸入相结合,对潜水员的心血管功能有轻微的影响.
- 这项研究强调了水手在血压,心率和动脉功能方面的特定变化.
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