分工和合作:纳米石电解和纳米封闭化,以消除抗生素耐药性基因
Zirong Chen1, Yihao Xiao1, Wanbin Li1
1College of Environment and Climate, Jinan University, Guangzhou 511443, PR China.
Water research
|August 17, 2025
概括
一种新的纳米石电解策略有效地从水中去除细胞内抗生素耐药性基因 (i-ARG). 这种方法使用纳米封闭来降解i-ARG,在水净化方面取得了重大进展.
科学领域:
- 环境科学 环境科学
- 纳米技术 纳米技术
- 水处理 处理水的方法
背景情况:
- 由于不有效的化,细胞内抗生素耐药性基因 (i-ARG) 存在于饮用水中.
- 细胞屏障防止消毒剂到达并降解微生物中的i-ARG.
研究的目的:
- 开发一种有效的方法来从水中消除i-ARG.
- 克服传统化在降解细胞内ARGs方面的局限性.
主要方法:
- 纳米 - 电解和纳米封闭 (Cl2) 的联合策略.
- 采用纳米 dendrites 与 mesoporous nanotips 进行增强的细胞可访问性和丰富.
- 在树突纳米片中利用增强电场来改善电穿孔和透.
主要成果:
- 实现了超高i-ARG去除 (4.5-log,99.997%) 的超快速速度 (13.1 log mM-1 min-1).
- 与传统的方法相比,证明了3.3-log的改善和6倍更快的降解.
- 在自来水中展示了长期的稳定性和可靠性,完全消除了i-ARG,并减少了副产品和能源消耗.
结论:
- 纳米石电解策略为减轻水中的ARG提供了一个高效和可适应的解决方案.
- 这种方法显著提高了消毒对细胞内ARG的有效性.
- 为先进的水处理技术铺平了道路,以打击抗菌素耐药性.
更多相关视频
相关概念视频
Antibiotic Selection
55.3K
Overview
55.3K
Transformation
92
Microbial communities are dynamic environments where cell lysis releases free DNA into the surroundings. Other cells can take up this extracellular DNA through a process known as transformation.When a cell incorporates this foreign DNA into its genome, resulting in genetic modification, the process is known as transformation. Cells capable of this process are termed competent. Competence can be natural, as observed in certain bacteria and archaea, or artificially induced in the...
92
Development of Antibiotic Resistance
197
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
197


