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Updated: Sep 11, 2025

High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds
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High-resolution Respirometry to Measure Mitochondrial Function of Intact Beta Cells in the Presence of Natural Compounds

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拉穆卢斯·莫里 (Sangzhi) 类化合物通过向CD81/内分泌网膜应激通路来增强胰腺β细胞的成熟和功能

Nan Wu1, Wenjing Zhang1, Sunyue He1

  • 1Department of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Phytomedicine : international journal of phytotherapy and phytopharmacology
|August 17, 2025
PubMed
概括

拉穆卢斯·莫里化物 (SZ-A) 通过促进β细胞成熟,改善2型糖尿病中的葡萄糖代谢. SZ-A抑制CD81,减少ER压力和增强胰岛素分泌,提供了一个新的治疗点.

关键词:
在CD81 CD81细胞内膜网膜应激压力拉穆卢斯·莫里 (桑吉) 化物 (SZ-A)在β细胞中,β细胞的功能.在β细胞成熟过程中.

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