与DCE-MRI相结合的IVIM描述了在乳房镜上检测到的架构扭曲:试点研究
Deshuo Dong1, Anliang Chen2, Ning Ning1
1Department of Radiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Road, Dalian, Liaoning 116011, PR China.
Magnetic resonance imaging
|August 17, 2025
概括
素不连贯运动 (IVIM) MRI 与动态对比增强MRI (DCE-MRI) 结合,可以准确地区分良性和恶性结构扭曲 (AD) 变化. 这种综合方法提供了高的诊断效果,使得可靠的排除恶性瘤在阿尔茨海默病患者.
科学领域:
- 放射学和医学成像学 医学成像学
- 在瘤学瘤学.
- 乳房成像 乳房成像
背景情况:
- 哺乳镜上建筑扭曲 (AD) 是一个诊断挑战,通常需要进一步的成像评估.
- 区分良性和恶性AD对于适当的患者管理和避免不必要的活检至关重要.
研究的目的:
- 为了评估结合intravoxel不连贯运动 (IVIM) MRI与动态对比增强MRI (DCE-MRI) 的诊断性能,以分类AD变化.
- 评估IVIM和DCE-MRI参数在区分良性AD和恶性AD的有用性.
主要方法:
- 在2019年4月至2022年2月期间,对80名乳腺核磁共振成像患者的乳腺核磁共振成像数据进行了回顾性分析.
- 两位放射科医生独立评估了DCE-MRI特征和IVIM参数 (ADC,D,D*,f).
- 通过病理学或至少两年的随访来确认最终诊断.
主要成果:
- 在58.75%的患者中,MRI检测到病变;36.17%是良性的,63.83%是恶性的.
- 结合IVIM和DCE-MRI实现了0.984的曲线下的面积 (AUC),以区分良性和恶性AD.
- DCE-MRI特征 (损伤直径,形状,边缘,增强,TIC) 和IVIM参数 (ADC,D,D*,f) 在良性和恶性病变之间显示出显著的差异 (P <0.05).
结论:
- IVIM和DCE-MRI的组合显示出对AD变化的分类具有很高的诊断效果.
- 患有AD的患者的阴性乳腺MRI可以可靠地排除恶性瘤.
- IVIM和DCE-MRI是提高AD的诊断准确性的宝贵工具.
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