登革热中的眼部表现:系统性审查和元分析
Alden Xavier Haslam1, Maria Del Mar Tiffer Blandón1, Andrea Sarahí Rodríguez Castro2
1Hospital Escuela Alejandro Dávila Bolaños, Republic of Nicaragua.
American journal of ophthalmology
|August 17, 2025
概括
眼部表现影响近三分之一的登革热患者,常见症状包括眼后疼痛和视力模糊. 早期识别这些眼睛疾病对于在特有地区及时干预至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 登革热是一种广泛传播的病毒性疾病,具有各种系统性并发症.
- 登革热的眼部表现往往被忽视,尽管可能会导致视力受到威胁.
- 目前关于登革热相关眼病患病率和频谱的现有数据是可变的,需要综合.
研究的目的:
- 对登革热患者眼部表现的综合流行情况进行系统的审查和元分析.
- 描述与登革热相关的眼睛疾病的频谱,频率和临床意义.
- 为临床意识提供信息,并指导登革热流行地区的未来研究.
主要方法:
- 在PubMed,CINAHL和LILACS进行了全面的文献搜索.
- 包括观察性研究报告在登革热患者的眼部表现.
- 使用随机效应模型计算了聚合流行率估计,通过I2统计评估异质性.
主要成果:
- 在16项涉及11,426名患者的研究中,任何眼部表现的综合患病率为0.32 (95% CI:0.22-0.45).
- 常见的表现包括逆眼疼痛 (0.20),副结膜出血 (0.18),视力模糊 (0.11).
- 还报告了视网膜出血 (0.08),毛囊炎 (0.05) 和黄斑病 (0.04) 的患病率,观察到显著的异质性.
结论:
- 相当一部分登革热患者出现眼部表现,这强调了需要提高临床警的必要性.
- 研究中的显著异质性需要标准化眼科评估,以改善诊断和管理.
- 早期检测和干预对于预防登革热患者的视力损伤至关重要,尤其是在热带地区.
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