相关实验视频

Updated: Sep 11, 2025

Porcine Model of Infrarenal Abdominal Aortic Aneurysm
11:13

Porcine Model of Infrarenal Abdominal Aortic Aneurysm

Published on: November 21, 2019

9.5K

sIL-6R对大动脉动脉瘤的影响:来自FinnGen和GWAS的遗传证据

Mengmeng Wang1, Tianqi Teng2, Degang Mo2

  • 1Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong, China; Institute of Cardiovascular Disease, Qingdao University, Qingdao 266001, Shandong, China.

International journal of cardiology
|August 17, 2025
PubMed
概括

更高的可溶性互白素-6受体 (sIL-6R) 水平与大动脉动脉瘤 (AA) 的风险降低有关. 这项孟德尔随机化研究证实了保护性因果关系,表明了潜在的治疗点.

关键词:
大动脉动脉瘤是一个大动脉动脉瘤.心血管疾病是什么心血管疾病这是遗传证据.门德尔的随机化sIL-6RR的使用情况.

更多相关视频

Murine Model of Thoracic Aortic Dissection Induced by Oral β-Aminopropionitrile and Subcutaneous Angiotensin II Infusion05:31

Murine Model of Thoracic Aortic Dissection Induced by Oral β-Aminopropionitrile and Subcutaneous Angiotensin II Infusion

Published on: May 16, 2025

297
Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model09:32

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model

Published on: February 23, 2020

6.3K

相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
14.2K
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
25
Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
15.9K