比较预麻醉克洛尼丁和特兰胺酸对鼻整形术内手术内出血量的影响:一种机器学习方法
Zahra Asghari Varzaneh1, Akram Hemmatipour2, Hadi Kazemi-Arpanahi3
1Department of Computer Science and Media Technology, Sustainable Digitalisation Research Center, Malmö University, Malmö, Sweden.
Scientific reports
|August 17, 2025
概括
术前的克洛尼丁可以显著降低鼻膜整形期间的血液损失,而不是与特兰胺酸 (TXA) 或没有药物相比. 回归模型准确地预测血液损失,有助于手术规划和患者安全.
科学领域:
- 整形外科 整形外科 整形外科
- 手术瘤学手术瘤学
- 麻醉学 麻醉学
背景情况:
- 在手术期间输血管理对于患者的治疗结果和手术效率至关重要.
- 在鼻美术中尽量减少出血对于实现最佳的美观和功能结果至关重要.
- 手术前的药物可以潜在地减轻手术过程中流失的血液.
研究的目的:
- 为了研究手术前的克洛尼丁和胺酸 (TXA) 对鼻膜整形期间流血的影响.
- 为了比较克洛尼丁和TXA在减少手术出血方面的疗效.
- 评估各种回归模型在手术期间输血的预测准确度.
主要方法:
- 一项对120名鼻整形患者 (2019-2022) 的回顾性横截面研究.
- 使用线性回归,随机森林 (RF),支向量回归 (SVR),极端梯度增强 (XGBoost),梯度增强,和LASSO模型分析血液损失.
- 使用平均绝对误差 (MAE),平均平方误差 (MSE) 和R平方指标对模型性能进行比较.
主要成果:
- 线性和里奇回归模型在预测血液损失方面表现出卓越的性能.
- 估计血液损失为克隆丁112毫升,TXA132毫升,没有药物的血液损失为157毫升.
- 克洛尼丁与手术内流血损失的最显著减少有关.
结论:
- 手术前的克洛尼丁有效地减少了鼻整形期间的血液流失.
- 回归模型可以准确预测手术流血,提高患者的安全性.
- 减少流血改善了手术的可见性,并可能缩短手术的持续时间.
相关概念视频
01:30Epistaxis
259
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
259
01:16Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
564
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
564