在胃肠道癌症手术后,戴肯丘托是否有效治疗术后肠道功能障碍? 一个更新的随机对照试验的元分析
Hideki Kogo1,2, Akihisa Matsuda3, Yasuyuki Negishi2,4
1Department of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-Ku, Tokyo, 113-8603, Japan.
戴肯丘托 (DKT) 通过缩短癌症手术患者第一次浮的时间,适度改善术后肠道功能障碍. 需要进一步的高质量试验来证实DKT疗效的这些发现.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 药理学 药理学是指药理学的学科.
背景情况:
- 手术后肠道功能障碍是腹部手术后的常见并发症.
- 日本草药Daikenchuto (DKT) 已经显示出治疗这种疾病的潜力.
- 之前的研究由于纳入了低质量的试验,导致不确定的结果.
研究的目的:
- 为了评估术后戴肯丘托 (DKT) 给药对术后肠功能障碍的疗效.
- 在接受胃肠道癌症手术的患者中分析第一次术后浮的时间.
主要方法:
- 一项全面的文献搜索确定了真正的随机对照试验 (RCT) 到2025年4月.
- 分析使用随机效应模型来评估到第一个空气流的平均时间差异.
- 分析包括了11个RCT,包括1413名患者.
主要成果:
- 术后DKT显著减少了第一次术后浮的时间 (MD: -0.19天,95%CI: -0.34至-0.04).
- 在研究之间没有观察到显著的异质性 (I2 = 26%).
- 亚组分析表明,在非结直肠手术,双盲,多机构和更大的研究中,疗效更大.
结论:
- DKT在改善术后肠道功能障碍方面表现出适度的益处,特别是加速第一个浮.
- 这些发现表明DKT在胃肠道癌症手术中的潜在实用性.
- 需要进一步进行高质量的RCT来巩固DKT疗效的证据.
更多相关视频
03:50Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
Published on: August 18, 2023
03:32Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
Published on: December 27, 2024
相关概念视频
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
