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Updated: Sep 11, 2025

Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions
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Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions

Published on: September 28, 2017

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使用原生质谱法剖析RNA和冠状病毒核体蛋白之间的相互作用

Virginia K James1, Olivia E Dioli1, Jennifer S Brodbelt1

  • 1Department of Chemistry, University of Texas at Austin, Austin, Texas 78712 United States.

Journal of the American Society for Mass Spectrometry
|August 18, 2025
PubMed
概括

这项研究揭示了SARS-CoV核体蛋白与RNA的相互作用,识别了双键位和比蛋白质-蛋白质相互作用更强的蛋白质-RNA相互作用. 这些发现增强了我们对病毒RNA包装机制的理解.

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