营养不良对儿科人口中瞳孔反应的影响
Dilara Özkoyuncu Kocabas1, Fuat Yavrum2, Elmas Yüksel Şükün3
1Ophthalmology Department, TOBB Economics and Technology University Faculty of Medicine, Ankara, Turkey.
European journal of ophthalmology
|August 18, 2025
概括
与健康儿童相比,营养不良儿童的瞳孔尺寸较小,瞳孔膨胀速度较快,这表明潜在的自主神经系统功能障碍. 这突显了营养不良对儿科患者眼睛反应的影响.
科学领域:
- 眼科医生 眼科 眼科
- 儿科 儿科 儿科
- 营养科学 营养科学
背景情况:
- 营养状况显著影响整体健康,包括神经和生理功能.
- 瞳孔反应是自主神经系统功能的敏感指标.
- 儿童营养不良可能导致各种健康并发症,可能会影响眼睛的参数.
研究的目的:
- 评估营养状况对5至18岁儿童瞳孔光反射的影响.
- 为了比较营养不良和健康儿童之间的瞳孔反应.
- 调查营养标志物和瞳孔行为之间的相关性.
主要方法:
- 一项涉及92名营养不良和80名健康儿童 (5-18岁) 的横截面研究.
- 评估血清费里,血红蛋白,维生素D和B12水平.
- 自动瞳孔测量 (Sirius拓) 测量静态 (scotopic, mesopic, photopic) 和动态的瞳孔反应.
- 在10秒内计算瞳孔膨胀速度.
主要成果:
- 营养不良儿童的血红蛋白,费里丁,维生素D和B12水平明显降低 (p < 0.001).
- 营养不良组在所有发光条件下显示出较小的平均瞳孔直径和更高的瞳孔膨胀速度 (p < 0.05).
- 体重指数 (BMI) 的z-score与美索比/光托比瞳孔直径正相关,与瞳孔膨胀速度负相关 (p < 0.05).
结论:
- 营养不良的儿童表现出改变的瞳孔反应,其特点是瞳孔尺寸减少和扩张速度增加.
- 这些发现表明,儿童营养不良的自主功能受损.
- 营养状况是影响儿童瞳孔动态和自主调节的关键因素.
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