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从与脂氧酶通路相关的 lncRNA 开发风险预测模型 (ProlncSig),用于预测乳腺癌的预后

Xiaoyu Fu1,2, Weixing Wang3, Bradley M Downs4

  • 1Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, China.

RNA biology
|August 18, 2025
PubMed
概括

这项研究开发了ProlncSig,一种新型模型使用与脂氧化酶通路相关的长非编码RNA (lncRNAs) 来预测乳腺癌预后并指导免疫疗法策略.

关键词:
免疫治疗是一种免疫疗法.脂氧基因酶的使用方法这是一个LncRNARNA.乳腺癌 乳腺癌 乳腺癌预后签名 预测签名瘤免疫力 免疫力

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lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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