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相关概念视频

Anatomy of the Ear01:16

Anatomy of the Ear

8.9K
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
8.9K
The Cochlea01:13

The Cochlea

45.9K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
45.9K
Auditory Pathway01:15

Auditory Pathway

5.8K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
5.8K
Assessing Body Temperature - Tympanic membrane01:14

Assessing Body Temperature - Tympanic membrane

668
Assessing tympanic membrane temperature involves using a tympanic membrane thermometer (TMT). Here is a step-by-step guide:
Step 1: Begin by practicing good hand hygiene to prevent the transmission of microorganisms.
Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
Step 3: Slide the probe cover in place to prevent cross-contamination.
Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...
668
Unrenewable Cells00:50

Unrenewable Cells

2.4K
In humans, the photoreceptor cells of the eye and sensory hair cells of the ear lack stem cells. These cells are thus unrenewable and cannot be replaced when they are damaged or destroyed.
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of...
2.4K
Hair Cells01:22

Hair Cells

41.3K
Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
41.3K

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Short-Term Complications Are Rare After Cholesteatoma Surgery.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·2026
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White Matter Tracts of the Auditory Pathways in Experimental Unilateral Ear Canal Atresia.

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相关实验视频

Updated: Sep 11, 2025

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages
09:09

Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

Published on: April 11, 2025

834

绘制人类小膜再生模式的地图.

Elnaz Sepehri, Cecilia Engmér Berglin, Yan Liu

    Audiology & neuro-otology
    |August 18, 2025
    PubMed
    概括

    这项研究确定了所有人类耳膜 (TM) 区域的干细胞,显示出与状 (UPT) 的未连接部分相比,在状和状附近具有更大的再生能力. 这些发现为TM治疗提供了洞察力.

    科学领域:

    • 耳鼻喉科 耳鼻喉科 耳鼻喉科
    • 再生医学是一种再生医学.
    • 细胞生物学 细胞生物学

    背景情况:

    • 慢性 tympanic 膜 (TM) 穿孔往往无法治愈,基础细胞机制不太了解.
    • 关于人类TM再生潜力的有限的大规模研究存在.
    • 了解TM干细胞局部化对于解决无法愈合的穿孔至关重要.

    研究的目的:

    • 在人类TM中绘制潜在的干细胞.
    • 评估TM角质细胞在不同TM区域 (maleus,annulus,UPT) 和解剖层次的再生能力.
    • 为了研究TM治疗的细胞基础.

    主要方法:

    • 用免疫组织化学 (IHC) 检测干细胞标记物 (α6和β1整合素,CK19,p63) 和增殖标记物 (Ki-67) 来采集和染色人类TM.
    • 盲目观察者进行半定量评分,评估标记物的流行率和强度.
    • 评估了评价者之间的可靠性,并分析了群体差异.

    主要成果:

    • 在所有TM区域 (maleus,annulus,UPT) 检测到干细胞标记物和Ki-67.
    • 与UPT相比,在annulus和maleus中观察到Ki-67和p63的更高流行率.
    • 在α6和CK19染色方面发现了明显的区域差异,在较低的解剖水平上发现了更高的强度.

    更多相关视频

    Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
    09:54

    Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

    Published on: May 10, 2019

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    In Ovo and Ex Ovo Methods to Study Avian Inner Ear Development
    10:09

    In Ovo and Ex Ovo Methods to Study Avian Inner Ear Development

    Published on: June 16, 2022

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    相关实验视频

    Last Updated: Sep 11, 2025

    Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages
    09:09

    Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages

    Published on: April 11, 2025

    834
    Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
    09:54

    Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

    Published on: May 10, 2019

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    In Ovo and Ex Ovo Methods to Study Avian Inner Ear Development
    10:09

    In Ovo and Ex Ovo Methods to Study Avian Inner Ear Development

    Published on: June 16, 2022

    2.5K

    结论:

    • 假定干细胞遍布人类的TM.
    • 骨和骨表现出比UPT更大的再生能力.
    • 这些发现为TM干细胞的局部化和多样性建立了基线,为未来关于TM穿孔愈合的研究提供了信息.