A-IIIROSAMPK/mTOR

Jianjian Wu1,2, Juntao Li1,2, Qiang Guo1,2

  • 1Department of Urology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, China.

概括

蒂莫沙宁A-III (TAIII) 通过诱导反应性氧物种 (ROS) 依赖的亡并通过AMPK/mTOR通路激活自,有效地抑制前列腺癌 (PCa) 细胞生长. 将TAIII与黄素 (CQ) 结合起来,可以增强其体内抗癌效应.

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