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Updated: Sep 11, 2025

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
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[关于端粒酶逆转录酶对缓解多克索鲁素诱导心脏毒性的作用的研究]

Qingqing Gu1, Qianwe Chen1, Yu Wang1

  • 1Department of Cardiology, the Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu, China.

Zhonghua wei zhong bing ji jiu yi xue
|August 18, 2025
PubMed
概括

过度表达端粒酶逆转录酶 (TERT) 通过降低心肌细胞亡和纤维化来防止多克索鲁比 (DOX) 诱导的心脏毒性. 这种方法改善了心脏功能,为化疗引起的心脏损伤提供了潜在的治疗策略.

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