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Updated: Sep 11, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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在先天性免疫反应中,通过dectin-1和β-glucan相互作用诱导CD83表达的机制

Naoki Arima1, Tsuyoshi Kato1, Takashi Kanno1

  • 1Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.

Immunology and cell biology
|August 18, 2025
PubMed
概括

人类单细胞dectin-1与β-glucan的相互作用调高了CD83的表达,这对免疫调节至关重要. 不溶性β-葡萄糖更有效,涉及NFκB和NFAT通路,提供有关真菌感染和自身免疫疾病的见解.

关键词:
这是一种CD83表达式.贝塔-葡萄糖是一种β-葡萄糖.德克丁-1-1是一种免疫调节 免疫调节激活T细胞的核因子.核因子-卡帕 B B 核因子

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