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为了对临床药理学影响的定量理解:人口药动力学建模

Donghong Xu1, Hanbin Li2, Stephen B Heitner3

  • 1Clinical Pharmacology, Cytokinetics, South San Francisco, California, USA.

CPT: pharmacometrics & systems pharmacology
|August 18, 2025
PubMed
概括

阿菲卡门特是一种心脏肌肉酶抑制剂,用于过度缩放性心肌病 (HCM),显示出可预测的药理动力学. 体重,性别和健康状况会影响胺暴露,但变化率仍然很低.

关键词:
心血管疾病心血管疾病临床试验是指临床试验中的临床试验.抑制剂 抑制剂 抑制剂建模建模模型是什么人口的药理动力学模拟模拟是指一个模拟模拟.

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